Abstract. Most of the medieval scholars in the article had encyclopedic knowledge. They were well versed in many sciences, including medicine. Analysis of many data in the field of medicine, which has a rich history, in the works of representatives of medical science of the Karakhanid period Muhammad al-Kaloniysi, al-Marwazi, Najibuddin Samarkandi, al-Razi and representatives of this field, methods of treatment, attention is paid to the analysis of data on the diagnosis, surgery and treatment of various diseases prepared from medicinal plants.